Off-screen, Ramírez announced they were bisexual in 2016 after hearing about the ongoing violence in the LGBTQ+ community, including the Orlando Pulse club shooting which killed 49 people, many LGBTQ+ people of Latino descent, per NBC News.
In 2020, Ramírez came out as nonbinary in an Instagram post, writing, “In me is the capacity to be Girlish boy Boyish girl Boyish boy Girlish girl All Neither #nonbinary“
Fans admired the announcement and shared their love on the post. A fan commented “I do see freedom, confidence, love and power in this face!!” Another wrote, “You’re amazing, so happy that you feel free to be you!”
Ramírez used to use the pronouns she/they, yet according to Out, Ramírez updated their pronouns to they/them. During an Out100 honoree celebration online, Grey’s Anatomy alum said “Hi, my name is Sara Ramírez, my pronouns are they/them/theirs, and I am an Out100 honoree for the entertainment category!”